![]() Dosage Conversion: Raw to Herbal Extract ConversionIntroductionHerbal decoction is the traditional method of administration of Chinese herbs in which the patient needs to prepare and drink the herbal decoction several times daily. This traditional method, however, is becoming more and more unacceptable in many modern life-styles due to such reasons as time-consumption, bitter taste, and unpleasant smell. These reasons contribute directly to poor patient compliance and lower effectiveness of the prescribed herbal formula. Herbal extracts, in comparison to herbal decoctions, are much more “patient-friendly.” Herbal extracts are available in fine granules and capsules - all ready for immediate use without further preparation, thus circumventing the disadvantages associated with herbal decoctions. And for patients who dislike the taste of herbal decoctions, herbal extracts are also available in capsules and tablets which “hide” the unpleasant taste. These advantages of herbal extracts are linked directly to a dramatic increase in patient compliance and an overall augmentation of clinical effectiveness. Because herbal extracts are more concentrated than bulk or raw herbs, administration of a small amount of herbal extracts mirrors the clinical effectiveness of a large amount of herbal decoctions. When switching from herbal decoction to herbal extracts, it is necessary to convert the dosage of each ingredient to ensure equivalent clinical response. Techniques for converting dosages are described in the following two sections. Dosage Conversion for Herbal FormulasThe standard adult dosage of herbal extracts is 4.5-6 grams per day (1-2 Evergreen spoons or 3-4 capsules, three times a day), taken on an empty stomach in three equally-divided doses. Standard herbal formulas are ready for immediate use and do not require any special handling or preparation. In cases where one formula may not be sufficient to effectively treat the patient, two formulas may be combined. For example, for a patient who has qi and blood deficiencies, one may choose to use both Si Jun Zi Tang (Four Gentlemen Combination) and Si Wu Tang (Tangkuei Four Combination) to tonify both qi and blood, respectively.
The same principles apply if one chooses to combine more than two formulas. The overall key to combining herbal formulas is to make sure the dosage for each ingredient is adjusted proportionally and the total daily dose equals to 6 grams per day. Dosage Conversion for Single HerbsThe concept of prescribing concentrated single herbs is exactly the same as prescribing bulk herbs. It may be slightly time-consuming to create a custom-made herbal formula, but the improved clinical outcome should justify the extra effort required. Dosage conversion from bulk or raw herbs to herbal extracts is as follows:
For example:
Step 1. Proportion of each herb:
Step 2. Daily dose of each herb:
Step 3. Total quantity of each herb:
The example listed above is a sample calculation of Ma Huang Tang (Ephedra Combination); and the calculation of all other formulas follows the same principle regardless of the number of herbs. Prescribing based on single herbs may require slightly more effort than herbal formulas for a practitioner; however, the dramatic improvement in patient compliance and overall augmentation of clinical effectiveness should easily justify the extra effort. |